loading...| Preferred Name |
Nalmefene Hydrochloride |
|
| Synonyms |
Nalmefene Hydrochloride NALMEFENE HYDROCHLORIDE Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, Hydrochloride,(5alpha)- Revex |
|
| Definitions |
The hydrochloride salt form of nalmefene, a naltrexone analogue with opioid antagonistic property. Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS. This results in reversal of the effects of the opioids, including reversal of analgesia, euphoria, respiratory depression, hypotension, sedation and physical dependence. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47631 |
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| CAS_Registry |
58895-64-0 |
|
| Chemical_Formula |
C21H25NO3.HCl |
|
| code |
C47631 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt form of nalmefene, a naltrexone analogue with opioid antagonistic property. Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS. This results in reversal of the effects of the opioids, including reversal of analgesia, euphoria, respiratory depression, hypotension, sedation and physical dependence. |
|
| FDA_UNII_Code |
K7K69QC05X |
|
| FULL_SYN |
Nalmefene Hydrochloride NALMEFENE HYDROCHLORIDE Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, Hydrochloride,(5alpha)- Revex |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Nalmefene Hydrochloride |
|
| Legacy Concept Name |
Nalmefene_Hydrochloride |
|
| Preferred_Name |
Nalmefene Hydrochloride |
|
| prefixIRI |
Thesaurus:C47631 |
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| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0771297 |
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| subClassOf |