loading...| Preferred Name |
Mefenamic Acid |
|
| Synonyms |
2-((2,3-Dimethylphenyl)amino)benzoic Acid Anthranilic Acid, N-2,3-xylyl- MEFENAMIC ACID Mefenamic Acid Ponstel |
|
| Definitions |
An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47599 |
|
| CAS_Registry |
61-68-7 |
|
| Chemical_Formula |
C15H15NO2 |
|
| code |
C47599 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
|
| FDA_UNII_Code |
367589PJ2C |
|
| FULL_SYN |
2-((2,3-Dimethylphenyl)amino)benzoic Acid Anthranilic Acid, N-2,3-xylyl- MEFENAMIC ACID Mefenamic Acid Ponstel |
|
| label |
Mefenamic Acid |
|
| Legacy Concept Name |
Mefenamic_Acid |
|
| NSC Number |
94437 |
|
| Preferred_Name |
Mefenamic Acid |
|
| prefixIRI |
Thesaurus:C47599 |
|
| PubMedID_Primary_Reference |
2242038 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0025152 |
|
| subClassOf |