loading...| Preferred Name |
Malathion |
|
| Synonyms |
Succinic Acid, mercapto-, Diethyl Ester, S-ester with O,O-Dimethylphosphorodithioate Butanedioic Acid,((dimethoxyphosphinothioyl)thio)-, Diethyl Ester MALATHION Malathion Ovide |
|
| Definitions |
A synthetic phosphorous compound and cholinesterase inhibitor that is strictly used as a topical pediculicide. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, thereby allowing acetylcholine to accumulate at cholinergic synapses and enhancing cholinergic receptor stimulation. This eventually leads to the head lice's death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47593 |
|
| ALT_DEFINITION |
The organophosphorus agent malathion. |
|
| CAS_Registry |
121-75-5 |
|
| CHEBI_ID |
CHEBI:6651 |
|
| Chemical_Formula |
C10H19O6PS2 |
|
| code |
C47593 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 |
|
| Contributing_Source |
CDISC FDA |
|
| DEFINITION |
A synthetic phosphorous compound and cholinesterase inhibitor that is strictly used as a topical pediculicide. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, thereby allowing acetylcholine to accumulate at cholinergic synapses and enhancing cholinergic receptor stimulation. This eventually leads to the head lice's death. |
|
| FDA_UNII_Code |
U5N7SU872W |
|
| FULL_SYN |
Succinic Acid, mercapto-, Diethyl Ester, S-ester with O,O-Dimethylphosphorodithioate Butanedioic Acid,((dimethoxyphosphinothioyl)thio)-, Diethyl Ester MALATHION Malathion Ovide |
|
| label |
Malathion |
|
| Legacy Concept Name |
Malathion |
|
| NSC Number |
6524 |
|
| Preferred_Name |
Malathion |
|
| prefixIRI |
Thesaurus:C47593 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Hazardous or Poisonous Substance |
|
| UMLS_CUI |
C0024547 |
|
| subClassOf |