loading...| Preferred Name |
Loracarbef |
|
| Synonyms |
(6R, 7S)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Monohydrate LORACARBEF Lorabid Loracarbef |
|
| Definitions |
A semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic derived from cephasporium. The bactericidal activity of loracarbef results from the inhibition of bacterial cell wall synthesis through interference with the cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and causes cell lysis. Loracarbef is more active against a variety of gram-negative organisms but less active against gram-positive pathogens compared to first-generation agents. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47588 |
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| CAS_Registry |
121961-22-6 |
|
| Chemical_Formula |
C16H16ClN3O4.H2O |
|
| code |
C47588 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic derived from cephasporium. The bactericidal activity of loracarbef results from the inhibition of bacterial cell wall synthesis through interference with the cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and causes cell lysis. Loracarbef is more active against a variety of gram-negative organisms but less active against gram-positive pathogens compared to first-generation agents. |
|
| FDA_UNII_Code |
3X11EVM5SU |
|
| FULL_SYN |
(6R, 7S)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Monohydrate LORACARBEF Lorabid Loracarbef |
|
| label |
Loracarbef |
|
| Legacy Concept Name |
Loracarbef |
|
| Preferred_Name |
Loracarbef |
|
| prefixIRI |
Thesaurus:C47588 |
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| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0721422 |
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| subClassOf |