loading...| Preferred Name |
Halcinonide |
|
| Synonyms |
Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)- 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone Halcinonide HALCINONIDE Halciderm Halcort Halog Volog |
|
| Definitions |
A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47552 |
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| CAS_Registry |
3093-35-4 |
|
| Chemical_Formula |
C24H32ClFO5 |
|
| code |
C47552 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) |
|
| FDA_UNII_Code |
SI86V6QNEG |
|
| FULL_SYN |
Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)- 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone Halcinonide HALCINONIDE Halciderm Halcort Halog Volog |
|
| label |
Halcinonide |
|
| Legacy Concept Name |
Halcinonide |
|
| Preferred_Name |
Halcinonide |
|
| prefixIRI |
Thesaurus:C47552 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0733757 |
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| subClassOf |