National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fluphenazine

Synonyms

FLUPHENAZINE

Fluphenazine

fluphenazine

1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI)

Definitions

A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47536

ALT_DEFINITION

A drug that is used to treat mental and emotional disorders and is being studied in the treatment of multiple myeloma. Fluphenazine may stop tumor growth by keeping myeloma cells from dividing and causing them to die. It is a type of antipsychotic.

CAS_Registry

69-23-8

CHEBI_ID

CHEBI:5123

Chemical_Formula

C22H26F3N3OS

code

C47536

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia.

FDA_UNII_Code

S79426A41Z

FULL_SYN

FLUPHENAZINE

Fluphenazine

fluphenazine

1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI)

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47996

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47995

label

Fluphenazine

Legacy Concept Name

Fluphenazine

NSC Number

62323

Preferred_Name

Fluphenazine

prefixIRI

Thesaurus:C47536

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0016368

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29710

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http://purl.obolibrary.org/obo/CHEBI_5123 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 FYPO LOOM
http://www.case.edu/EpilepsyOntology.owl#Fluphenazine EPSO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 CHEBI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005476 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147853 NDFRT LOOM
http://scai.fraunhofer.de/AlzheimerOntology#fluphenazine ADO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147853 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147853 CIDO LOOM
http://purl.bioontology.org/ontology/VANDF/4019762 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/x004h RCD LOOM
http://purl.bioontology.org/ontology/SNMI/C-62A20 SNMI LOOM
http://purl.bioontology.org/ontology/LNC/LP16152-8 LOINC LOOM
http://www.drugbank.ca/drugs/DB00623 FTC LOOM
https://go.drugbank.com/drugs/DB00623 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5133 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/001473 NDDF LOOM
http://purl.bioontology.org/ontology/ATC/N05AB02 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_5123 CIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.369.326 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Fluphenazine GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372730004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/MESH_D005476 BERO LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass1ba036ea_cd34_4f5c_825f_7a4458060356 WWECA LOOM
http://purl.obolibrary.org/obo/NCIT_C47536 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D005476 MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0006685 OMIT LOOM
http://purl.jp/bio/4/id/200906076338832918 IOBC LOOM
http://www.case.edu/EpSO.owl#Fluphenazine MEPO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017394 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/CSP/2264-5314 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060471 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0016368 OCHV LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Fluphenazine APAONTO LOOM
http://purl.bioontology.org/ontology/RXNORM/4496 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907036971811298 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.741.326 RH-MESH LOOM