loading...| Preferred Name |
Felbamate |
|
| Synonyms |
Carbamic Acid, 2-phenyltrimethylene Ester 2-Phenyl-1,3-propanediol Dicarbamate FELBAMATE Felbamate Felbatol |
|
| Definitions |
A propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47530 |
|
| CAS_Registry |
25451-15-4 |
|
| CHEBI_ID |
CHEBI:4995 |
|
| Chemical_Formula |
C11H14N2O4 |
|
| code |
C47530 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory. |
|
| FDA_UNII_Code |
X72RBB02N8 |
|
| FULL_SYN |
Carbamic Acid, 2-phenyltrimethylene Ester 2-Phenyl-1,3-propanediol Dicarbamate FELBAMATE Felbamate Felbatol |
|
| label |
Felbamate |
|
| Legacy Concept Name |
Felbamate |
|
| Preferred_Name |
Felbamate |
|
| prefixIRI |
Thesaurus:C47530 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0060135 |
|
| subClassOf |