loading...| Preferred Name |
Etomidate |
|
| Synonyms |
1H-Imidazole-5-Carboxylic Acid, 1-((1R)-1-phenylethyl)-, Ethyl Ester R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate Amidate ETOMIDATE Etomidate |
|
| Definitions |
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47527 |
|
| CAS_Registry |
33125-97-2 |
|
| CHEBI_ID |
CHEBI:4910 |
|
| Chemical_Formula |
C14H16N2O2 |
|
| code |
C47527 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 |
|
| Contributing_Source |
CPTAC FDA |
|
| DEFINITION |
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization. |
|
| FDA_UNII_Code |
Z22628B598 |
|
| FULL_SYN |
1H-Imidazole-5-Carboxylic Acid, 1-((1R)-1-phenylethyl)-, Ethyl Ester R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate Amidate ETOMIDATE Etomidate |
|
| label |
Etomidate |
|
| Legacy Concept Name |
Etomidate |
|
| Preferred_Name |
Etomidate |
|
| prefixIRI |
Thesaurus:C47527 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0015131 |
|
| subClassOf |