loading...| Preferred Name |
Eptifibatide |
|
| Synonyms |
Eptifibatide EPTIFIBATIDE L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide Integrilin |
|
| Definitions |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47516 |
|
| CAS_Registry |
148031-34-9 188627-80-7 |
|
| CHEBI_ID |
CHEBI:291902 |
|
| Chemical_Formula |
C35H49N11O9S2 |
|
| code |
C47516 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development. |
|
| FDA_UNII_Code |
NA8320J834 |
|
| FULL_SYN |
Eptifibatide EPTIFIBATIDE L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide Integrilin |
|
| label |
Eptifibatide |
|
| Legacy Concept Name |
Eptifibatide |
|
| Preferred_Name |
Eptifibatide |
|
| prefixIRI |
Thesaurus:C47516 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0253563 |
|
| subClassOf |