National Cancer Institute Thesaurus

Last uploaded: February 25, 2019
Preferred Name

Desflurane

Synonyms

Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-

Desflurane

DESFLURANE

Suprane

I 653

Definitions

A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matrix of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47472

CAS_Registry

57041-67-5

CHEBI_ID

CHEBI:4445

Chemical_Formula

C3H2F6O

code

C47472

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matrix of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

FDA_UNII_Code

CRS35BZ94Q

FULL_SYN

Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-

Desflurane

DESFLURANE

Suprane

I 653

label

Desflurane

Legacy_Concept_Name

Desflurane

PDQ_Closed_Trial_Search_ID

574264

PDQ_Open_Trial_Search_ID

574264

Preferred_Name

Desflurane

prefixIRI

ncit:C47472

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0063252

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C245

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#C053562 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/C053562 MESH LOOM
http://purl.obolibrary.org/obo/DRON_00013063 DRON LOOM
http://purl.bioontology.org/ontology/RCD/o28.. RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108393001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148295 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386841003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU050116 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 NIFSTD LOOM
http://purl.bioontology.org/ontology/LNC/LP101882-1 LOINC LOOM
http://www.drugbank.ca/drugs/DB01189 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4020649 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/N01AB07 ATC LOOM
http://www.co-ode.org/ontologies/galen#Desflurane GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/27340 RXNORM LOOM