National Cancer Institute Thesaurus

Last uploaded: May 28, 2019
Preferred Name

Chlordiazepoxide

Synonyms

Chlordiazepoxide

3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl, 4-oxide

Librelease

CHLORDIAZEPOXIDE

Libritabs

Definitions

A long-acting benzodiazepine with anxiolytic, sedative and hypnotic activity. Chlordiazepoxide exerts its effect by binding to the benzodiazepine site at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47443

CAS_Registry

58-25-3

CHEBI_ID

CHEBI:3611

Chemical_Formula

C16H14ClN3O

code

C47443

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A long-acting benzodiazepine with anxiolytic, sedative and hypnotic activity. Chlordiazepoxide exerts its effect by binding to the benzodiazepine site at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS.

FDA_UNII_Code

6RZ6XEZ3CR

FULL_SYN

Chlordiazepoxide

3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl, 4-oxide

Librelease

CHLORDIAZEPOXIDE

Libritabs

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47973

label

Chlordiazepoxide

Legacy_Concept_Name

Chlordiazepoxide

Preferred_Name

Chlordiazepoxide

prefixIRI

ncit:C47443

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0008188

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1012

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http://purl.bioontology.org/ontology/RCD/d24.. RCD LOOM
http://purl.bioontology.org/ontology/LNC/LP16068-6 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002707 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017780 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372866006 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-64530 SNMI LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006722 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/N05BA02 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D002707 MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Chlordiazepoxide APAONTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3611_1 NIFSTD LOOM
http://purl.bioontology.org/ontology/CSP/0314-4236 CRISP LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3611 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146141 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907018052044924 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.079.080.150 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00475 FTC LOOM
http://purl.bioontology.org/ontology/RXNORM/2356 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Chlordiazepoxide GALEN LOOM
http://purl.jp/bio/4/id/200906045687860667 IOBC LOOM