loading...| Preferred Name |
Ceforanide |
|
| Synonyms |
(6R-trans)-7-(((2-(Aminomethyl)phenyl)acetyl)amino)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid CEFORANIDE Ceforanide Precef |
|
| Definitions |
A semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47436 |
|
| CAS_Registry |
60925-61-3 |
|
| CHEBI_ID |
CHEBI:3495 |
|
| Chemical_Formula |
C20H21N7O6S2 |
|
| code |
C47436 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis. |
|
| FDA_UNII_Code |
8M1YF8951V |
|
| FULL_SYN |
(6R-trans)-7-(((2-(Aminomethyl)phenyl)acetyl)amino)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid CEFORANIDE Ceforanide Precef |
|
| label |
Ceforanide |
|
| Legacy Concept Name |
Ceforanide |
|
| Preferred_Name |
Ceforanide |
|
| prefixIRI |
Thesaurus:C47436 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0055008 |
|
| subClassOf |