National Cancer Institute Thesaurus

Last uploaded: July 29, 2019
Preferred Name

Aripiprazole

Synonyms

2(1H)-Quinolinone, 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-

Aripiprazole

Opc 14597

ARIPIPRAZOLE

Abilify

Definitions

A quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent antagonistic activity on serotonin 5-HT2A receptors. This drug stabilizes dopamine and serotonin activity in the limbic and cortical system. Aripiprazole is used in managing symptoms of schizophrenia and of acute manic and mixed episodes associated with bipolar I disorders.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47403

Accepted_Therapeutic_Use_For

Major Depressive Disorder

CAS_Registry

129722-12-9

CHEBI_ID

CHEBI:31236

Chemical_Formula

C23H27Cl2N3O2

code

C47403

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent antagonistic activity on serotonin 5-HT2A receptors. This drug stabilizes dopamine and serotonin activity in the limbic and cortical system. Aripiprazole is used in managing symptoms of schizophrenia and of acute manic and mixed episodes associated with bipolar I disorders.

FDA_UNII_Code

82VFR53I78

FULL_SYN

2(1H)-Quinolinone, 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-

Aripiprazole

Opc 14597

ARIPIPRAZOLE

Abilify

label

Aripiprazole

Legacy_Concept_Name

Aripiprazole

Preferred_Name

Aripiprazole

prefixIRI

ncit:C47403

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0299792

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29710

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http://stirdf.jst.go.jp/id/200907049652412997 IOBC LOOM
http://stirdf.jst.go.jp/id/200907049652412997 IOBC LOOM
http://stirdf.jst.go.jp/id/200907049652412997 IOBC LOOM
http://purl.jp/bio/4/id/200906058719484500 IOBC LOOM
http://purl.jp/bio/4/id/200906058719484500 IOBC LOOM
http://purl.jp/bio/4/id/200906058719484500 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D000068180 MESH LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005060 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005060 DMTO LOOM
http://purl.bioontology.org/ontology/UATC/N05AX12 ATC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004322 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004322 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004322 DMTO LOOM
http://purl.bioontology.org/ontology/NDDF/009852 NDDF LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 NIFSTD LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Aripiprazole APAONTO LOOM
http://doe-generated-ontology.com/OntoAD#C0299792 ONTOAD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C094645 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/406784005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4021367 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP34967-7 LOINC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005452 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005452 DMTO LOOM
http://www.semanticweb.org/dellvostro3750/ontologies/2018/2/untitled-ontology-10#aripiprazole HP_O LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148786 NDFRT LOOM
http://www.case.edu/EpSO.owl#Aripiprazole EPSO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU017703 LOINC LOOM
http://scai.fraunhofer.de/AlzheimerOntology#aripiprazole ADO LOOM
http://www.drugbank.ca/drugs/DB01238 FTC LOOM
http://purl.bioontology.org/ontology/RXNORM/89013 RXNORM LOOM