loading...| Preferred Name |
Aminosalicylic Acid |
|
| Synonyms |
p-Aminosalicylic Acid 4-Aminosalicylic Acid Benzoic Acid, 4-Amino-2-hydroxy- Aminosalicylic Acid AMINOSALICYLIC ACID NIH 2939 Pamisyl Parasal Paser |
|
| Definitions |
An analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylic acid exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47394 |
|
| CAS_Registry |
65-49-6 |
|
| CHEBI_ID |
CHEBI:27565 |
|
| Chemical_Formula |
C7H7NO3 |
|
| code |
C47394 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
An analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylic acid exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death. |
|
| FDA_UNII_Code |
5B2658E0N2 |
|
| FULL_SYN |
p-Aminosalicylic Acid 4-Aminosalicylic Acid Benzoic Acid, 4-Amino-2-hydroxy- Aminosalicylic Acid AMINOSALICYLIC ACID NIH 2939 Pamisyl Parasal Paser |
|
| Has_Salt_Form |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76468 |
|
| label |
Aminosalicylic Acid |
|
| Legacy Concept Name |
Aminosalicylic_Acid |
|
| NSC Number |
2083 |
|
| Preferred_Name |
Aminosalicylic Acid |
|
| prefixIRI |
Thesaurus:C47394 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0030125 |
|
| subClassOf |