National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Albendazole

Synonyms

Carbamic Acid,(5-(Propylthio)-1H-benzimidazol-2-yl)-, Methyl Ester

Albendazole

ALBENDAZOLE

Albenza

Bilutac

Proftril

SKF 62979

Zentel

Definitions

A broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47384

CAS_Registry

54965-21-8

CHEBI_ID

CHEBI:16664

Chemical_Formula

C12H15N3O2S

code

C47384

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections. (NCI05)

FDA_UNII_Code

F4216019LN

FULL_SYN

Carbamic Acid,(5-(Propylthio)-1H-benzimidazol-2-yl)-, Methyl Ester

Albendazole

ALBENDAZOLE

Albenza

Bilutac

Proftril

SKF 62979

Zentel

label

Albendazole

Legacy Concept Name

Albendazole

NCI_Drug_Dictionary_ID

798650

NSC Number

220008

PDQ_Closed_Trial_Search_ID

798650

PDQ_Open_Trial_Search_ID

798650

Preferred_Name

Albendazole

prefixIRI

Thesaurus:C47384

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0001911

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C250

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http://purl.obolibrary.org/obo/CHEBI_16664 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 CHEBI LOOM
http://purl.obolibrary.org/obo/ARO_3007090 ARO LOOM
http://purl.obolibrary.org/obo/MESH_D015766 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_16664 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.103.070 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148464 NDFRT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016365 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387558006 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C47384 BERO LOOM
http://purl.bioontology.org/ontology/RCD/es2.. RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0001911 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#856 OCHV LOOM
http://stirdf.jst.go.jp/id/200907089299897703 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015766 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4020995 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D015766 MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00518 DINTO LOOM
http://purl.bioontology.org/ontology/SNMI/C-56B00 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.251.022 RH-MESH LOOM
http://purl.jp/bio/4/id/200906012095535822 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/P02CA03 ATC LOOM
https://go.drugbank.com/drugs/DB00518 MDM LOOM
http://purl.obolibrary.org/obo/OMIT_0016412 OMIT LOOM
http://purl.bioontology.org/ontology/RXNORM/430 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Albendazole GALEN LOOM
http://www.drugbank.ca/drugs/DB00518 FTC LOOM
http://purl.bioontology.org/ontology/NDDF/004079 NDDF LOOM