loading...| Preferred Name |
Dipyridamole |
|
| Synonyms |
DIPYRIDAMOLE 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol Dipyridamole dipyridamole DP Persantine |
|
| Definitions |
A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C445 |
|
| ALT_DEFINITION |
A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents. |
|
| CAS_Registry |
58-32-2 |
|
| CHEBI_ID |
CHEBI:4653 |
|
| Chemical_Formula |
C24H40N8O4 |
|
| code |
C445 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 |
|
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04) |
|
| FDA_UNII_Code |
64ALC7F90C |
|
| FULL_SYN |
DIPYRIDAMOLE 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol Dipyridamole dipyridamole DP Persantine |
|
| label |
Dipyridamole |
|
| Legacy Concept Name |
Dipyridamole |
|
| NCI_Drug_Dictionary_ID |
39229 |
|
| NSC Number |
515776 |
|
| PDQ_Closed_Trial_Search_ID |
39229 |
|
| PDQ_Open_Trial_Search_ID |
39229 |
|
| Preferred_Name |
Dipyridamole |
|
| prefixIRI |
Thesaurus:C445 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0012582 |
|
| subClassOf |