loading...| Preferred Name |
Dexamethasone |
|
| Synonyms |
Amplidermis Hexadecadrol Dexamonozon Alin Oftalmico Fortecortin Fluorodelta (11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione Gammacorten Dexamethasone Intensol Deltafluorene dexamethasone Mymethasone Dexa-Scheroson Dexamethasonum Visumetazone Lokalison-F 9Alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone Dexa-Mamallet Decadron DP Dexamethasone Aknichthol Dexa Desamethasone Auricularum Anemul mono Cortisumman 16Alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione Dexamecortin 9alpha-Fluoro-16alpha- methylprednisolone Fluoro-9alpha Methyl-16alpha Prednisolone Dexa-Rhinosan Cortidexason 16Alpha-methyl-9alpha-fluoroprednisolone 9Alpha-fluoro-16alpha-methylprednisolone Methylfluorprednisolone Decasone R.p. Millicorten DEXAMETHASONE 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone Dexafluorene Aacidexam Adexone Alba-Dex Alin Alin Depot Auxiloson Baycadron Baycuten Baycuten N Decacort Decadrol Decadron Decalix Decameth Dectancyl Dekacort Deronil Desameton Dexa-sine Dexacortal Dexacortin Dexafarma Dexalocal Dexameth Dexapos Dexinoral Dexone Dinormon Dxevo Hemady Hexadrol Loverine Orgadrone Spersadex TaperDex ZoDex |
|
| Definitions |
A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C422 |
|
| Accepted_Therapeutic_Use_For |
Allergic disorders; antiemetic; corneal injury; inflammatory conditions |
|
| ALT_DEFINITION |
A synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland). Dexamethasone is used to treat leukemia and lymphoma and may be used to treat some of the problems caused by other cancers and their treatment. |
|
| CAS_Registry |
50-02-2 |
|
| CHEBI_ID |
CHEBI:41879 |
|
| Chemical_Formula |
C22H29FO5 |
|
| code |
C422 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192234 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183082 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C183083 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186328 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186327 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186341 |
|
| Contributing_Source |
CTRP DIPG/DMG FDA GDC HemOnc OORO PCDC |
|
| DEFINITION |
A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04) |
|
| Display_Name |
Dexamethasone |
|
| FDA_UNII_Code |
7S5I7G3JQL |
|
| FULL_SYN |
Amplidermis Hexadecadrol Dexamonozon Alin Oftalmico Fortecortin Fluorodelta (11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione Gammacorten Dexamethasone Intensol Deltafluorene dexamethasone Mymethasone Dexa-Scheroson Dexamethasonum Visumetazone Lokalison-F 9Alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone Dexa-Mamallet Decadron DP Dexamethasone Aknichthol Dexa Desamethasone Auricularum Anemul mono Cortisumman 16Alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione Dexamecortin 9alpha-Fluoro-16alpha- methylprednisolone Fluoro-9alpha Methyl-16alpha Prednisolone Dexa-Rhinosan Cortidexason 16Alpha-methyl-9alpha-fluoroprednisolone 9Alpha-fluoro-16alpha-methylprednisolone Methylfluorprednisolone Decasone R.p. Millicorten DEXAMETHASONE 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone Dexafluorene Aacidexam Adexone Alba-Dex Alin Alin Depot Auxiloson Baycadron Baycuten Baycuten N Decacort Decadrol Decadron Decalix Decameth Dectancyl Dekacort Deronil Desameton Dexa-sine Dexacortal Dexacortin Dexafarma Dexalocal Dexameth Dexapos Dexinoral Dexone Dinormon Dxevo Hemady Hexadrol Loverine Orgadrone Spersadex TaperDex ZoDex |
|
| Has_Salt_Form |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C200708 |
|
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Dexamethasone |
|
| Legacy Concept Name |
Dexamethasone |
|
| Maps_To |
Dexamethasone |
|
| NCI_Drug_Dictionary_ID |
39789 |
|
| NSC Number |
34521 |
|
| PDQ_Closed_Trial_Search_ID |
39789 |
|
| PDQ_Open_Trial_Search_ID |
39789 |
|
| Preferred_Name |
Dexamethasone |
|
| prefixIRI |
Thesaurus:C422 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0011777 |
|
| subClassOf |