National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Dexamethasone

Synonyms

ZoDex

Decacort

Alin Depot

Dexameth

Dexafluorene

Baycadron

Amplidermis

Lokalison-F

Anemul mono

Decasone R.p.

Dexamethasone Intensol

Orgadrone

Desameton

Dekacort

Dexa-Scheroson

Aknichthol Dexa

Adexone

16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone

Dexapos

Dexa-sine

Hexadrol

Auxiloson

Dexacortal

dexamethasone

Dexamethasonum

Hexadecadrol

Dexamonozon

Decameth

Gammacorten

Dexamecortin

16Alpha-methyl-9alpha-fluoroprednisolone

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

9alpha-Fluoro-16alpha- methylprednisolone

Mymethasone

Desamethasone

Decadrol

9Alpha-fluoro-16alpha-methylprednisolone

TaperDex

Cortidexason

Fluoro-9alpha Methyl-16alpha Prednisolone

Dexinoral

Decadron DP

Dinormon

Deltafluorene

Alin

Methylfluorprednisolone

Loverine

9Alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

(11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

Fortecortin

Alba-Dex

16Alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione

Dexa-Rhinosan

Millicorten

Visumetazone

Dexa-Mamallet

Fluorodelta

Deronil

Spersadex

Aacidexam

Auricularum

Dexalocal

Dexone

Decadron

Baycuten N

Dexamethasone

Decalix

Alin Oftalmico

Dexacortin

Dectancyl

Baycuten

Cortisumman

DEXAMETHASONE

Dexafarma

Definitions

A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C422

Accepted_Therapeutic_Use_For

Allergic disorders; antiemetic; corneal injury; inflammatory conditions

ALT_DEFINITION

A synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland). Dexamethasone is used to treat leukemia and lymphoma and may be used to treat some of the problems caused by other cancers and their treatment.

CAS_Registry

50-02-2

CHEBI_ID

CHEBI:41879

Chemical_Formula

C22H29FO5

code

C422

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

FDA

DEFINITION

A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04)

Display_Name

Dexamethasone

FDA_UNII_Code

7S5I7G3JQL

FULL_SYN

ZoDex

Decacort

Alin Depot

Dexameth

Dexafluorene

Baycadron

Amplidermis

Lokalison-F

Anemul mono

Decasone R.p.

Dexamethasone Intensol

Orgadrone

Desameton

Dekacort

Dexa-Scheroson

Aknichthol Dexa

Adexone

16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone

Dexapos

Dexa-sine

Hexadrol

Auxiloson

Dexacortal

dexamethasone

Dexamethasonum

Hexadecadrol

Dexamonozon

Decameth

Gammacorten

Dexamecortin

16Alpha-methyl-9alpha-fluoroprednisolone

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

9alpha-Fluoro-16alpha- methylprednisolone

Mymethasone

Desamethasone

Decadrol

9Alpha-fluoro-16alpha-methylprednisolone

TaperDex

Cortidexason

Fluoro-9alpha Methyl-16alpha Prednisolone

Dexinoral

Decadron DP

Dinormon

Deltafluorene

Alin

Methylfluorprednisolone

Loverine

9Alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

(11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

Fortecortin

Alba-Dex

16Alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione

Dexa-Rhinosan

Millicorten

Visumetazone

Dexa-Mamallet

Fluorodelta

Deronil

Spersadex

Aacidexam

Auricularum

Dexalocal

Dexone

Decadron

Baycuten N

Dexamethasone

Decalix

Alin Oftalmico

Dexacortin

Dectancyl

Baycuten

Cortisumman

DEXAMETHASONE

Dexafarma

label

Dexamethasone

Legacy_Concept_Name

Dexamethasone

NSC_Code

34521

PDQ_Closed_Trial_Search_ID

39789

PDQ_Open_Trial_Search_ID

39789

Preferred_Name

Dexamethasone

prefixIRI

ncit:C422

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0011777

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C267

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http://purl.bioontology.org/ontology/UATC/D07AB19 ATC LOOM
http://purl.bioontology.org/ontology/UATC/C05AA09 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP32530-5 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/H02AB02 ATC LOOM
http://purl.obolibrary.org/obo/XCO_0000372 XCO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146273 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.432.769.344 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/S01BA01 ATC LOOM
http://purl.bioontology.org/ontology/CSP/0059-7733 CRISP LOOM
http://purl.bioontology.org/ontology/UATC/D10AA03 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.908.238 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP18549-3 LOINC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004511 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004511 DMTO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004621 LOINC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Dexamethasone APAONTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003907 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_41879 NIFSTD LOOM
http://purl.bioontology.org/ontology/UATC/S03BA01 ATC LOOM
http://stirdf.jst.go.jp/id/200907013999102683 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/D07XB05 ATC LOOM
http://bmi.utah.edu/ontologies/peontology/C0011777 RAO LOOM
http://purl.bioontology.org/ontology/UATC/S02BA06 ATC LOOM
http://purl.bioontology.org/ontology/UATC/S01CB01 ATC LOOM
http://purl.bioontology.org/ontology/UATC/R01AD03 ATC LOOM
http://www.co-ode.org/ontologies/galen#Dexamethasone GALEN LOOM
http://purl.bioontology.org/ontology/UATC/A01AC02 ATC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039789 PDQ LOOM
http://purl.bioontology.org/ontology/MESH/D003907 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017922 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372584003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RCD/x02M3 RCD LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146273 ODAE LOOM
http://purl.bioontology.org/ontology/RXNORM/3264 RXNORM LOOM
http://purl.jp/bio/4/id/200906065294692755 IOBC LOOM
http://www.drugbank.ca/drugs/DB01234 FTC LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_eac7fb6f_58b2_49c0_b6cc_a4436375cf48 CVAO LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_eac7fb6f_58b2_49c0_b6cc_a4436375cf48 STO-DRAFT LOOM