National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Substance-P Receptor

Synonyms

NK-1 Receptor

Substance P Receptor

Substance-P Receptor

Tachykinin Receptor 1

Tachykinin 1 Receptor

Neurokinin 1 Receptor

NK-1R

NK1R

NKIR

SPR

TAC1R

TACR1

Definitions

Substance-P receptor (407 aa, ~46 kDa) is encoded by the human TACR1 gene. This protein is involved in tachykinin-dependent G protein-coupled receptor signaling.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41023

code

C41023

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Substance-P receptor (407 aa, ~46 kDa) is encoded by the human TACR1 gene. This protein is involved in tachykinin-dependent G protein-coupled receptor signaling.

DesignNote

Substance-P receptor affinity for tachykinins from highest to lowest is: substance P, substance K, neuromedin K. (UniProt)

Display_Name

Substance-P Receptor

FULL_SYN

NK-1 Receptor

Substance P Receptor

Substance-P Receptor

Tachykinin Receptor 1

Tachykinin 1 Receptor

Neurokinin 1 Receptor

NK-1R

NK1R

NKIR

SPR

TAC1R

TACR1

label

Substance-P Receptor

Legacy Concept Name

Tachykinin_Receptor-1

OMIM_Number

162323

Preferred_Name

Substance-P Receptor

prefixIRI

Thesaurus:C41023

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

Swiss_Prot

P25103

UMLS_CUI

C0164209

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18239

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