loading...| Preferred Name |
Cefotaxime |
|
| Synonyms |
CEFOTAXIME Cefotaxime |
|
| Definitions |
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C354 |
|
| CAS_Registry |
63527-52-6 |
|
| CHEBI_ID |
CHEBI:204928 |
|
| Chemical_Formula |
C16H17N5O7S2 |
|
| code |
C354 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis. |
|
| FDA_UNII_Code |
N2GI8B1GK7 |
|
| FULL_SYN |
CEFOTAXIME Cefotaxime |
|
| Has_Salt_Form | ||
| label |
Cefotaxime |
|
| Legacy Concept Name |
Cefotaxime |
|
| NCI_Drug_Dictionary_ID |
39177 |
|
| PDQ_Closed_Trial_Search_ID |
39177 |
|
| PDQ_Open_Trial_Search_ID |
39177 |
|
| Preferred_Name |
Cefotaxime |
|
| prefixIRI |
Thesaurus:C354 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0007554 |
|
| subClassOf |