National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Capsaicin

Synonyms

N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide

(E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

CAPSAICIN

Capsaicin

capsaicin

Definitions

A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C339

ALT_DEFINITION

A component of certain plants, including cayenne and red pepper, used topically for peripheral nerve pain. Also being studied for controlling mucositis pain after chemotherapy and radiation therapy.

Capsaicinoid compound with side chain CO(CH2)4(CH)2CH(CH3)2. The chemical structure is CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC.

CAS_Registry

404-86-4

CHEBI_ID

CHEBI:3374

Chemical_Formula

C18H27NO3

code

C339

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis.

FDA_UNII_Code

S07O44R1ZM

FULL_SYN

N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide

(E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

CAPSAICIN

Capsaicin

capsaicin

label

Capsaicin

Legacy Concept Name

Capsaicin

NCI_Drug_Dictionary_ID

41591

NSC Number

56353

PDQ_Closed_Trial_Search_ID

41591

PDQ_Open_Trial_Search_ID

41591

Preferred_Name

Capsaicin

prefixIRI

Thesaurus:C339

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0006931

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68530

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2198

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3374 FOODON LOOM
http://purl.obolibrary.org/obo/XCO_0000897 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 CDNO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 CHEBI LOOM
http://purl.obolibrary.org/obo/OMIT_0003550 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.160.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1992 RXNORM LOOM
http://purl.bioontology.org/ontology/SNMI/C-30379 SNMI LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00857 COID LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.166.099 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 ODNAE LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147626 ODAE LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041591 PDQ LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147626 NDFRT LOOM
http://purl.obolibrary.org/obo/MESH_D002211 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.326.271.060.222 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002211 RH-MESH LOOM
http://purl.obolibrary.org/obo/ARO_3007360 ARO LOOM
http://purl.bioontology.org/ontology/VANDF/4019506 VANDF LOOM
http://purl.jp/bio/4/id/200906040660858480 IOBC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Capsaicin APAONTO LOOM
http://purl.bioontology.org/ontology/ATC/M02AB01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.760.200 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2373 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/N01BX04 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.251.355.325.190 RH-MESH LOOM
https://go.drugbank.com/drugs/DB06774 MDM LOOM
http://purl.bioontology.org/ontology/RCD/X7956 RCD LOOM
http://stirdf.jst.go.jp/id/200907014064989511 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006931 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C339 BERO LOOM
http://bmi.utah.edu/ontologies/peontology/C0006931 RAO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015990 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/95995002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D002211 MESH LOOM
http://purl.bioontology.org/ontology/CSP/4000-0137 CRISP LOOM