National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Capsaicin

Synonyms

capsaicin

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

(E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide

CAPSAICIN

Capsaicin

N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide

Definitions

A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C339

ALT_DEFINITION

Capsaicinoid compound with side chain CO(CH2)4(CH)2CH(CH3)2. The chemical structure is CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC.

A component of certain plants, including cayenne and red pepper, used topically for peripheral nerve pain. Also being studied for controlling mucositis pain after chemotherapy and radiation therapy.

CAS_Registry

404-86-4

CHEBI_ID

CHEBI:3374

Chemical_Formula

C18H27NO3

code

C339

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis.

FDA_UNII_Code

S07O44R1ZM

FULL_SYN

capsaicin

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

(E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide

CAPSAICIN

Capsaicin

N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide

label

Capsaicin

Legacy_Concept_Name

Capsaicin

NSC_Code

56353

PDQ_Closed_Trial_Search_ID

41591

PDQ_Open_Trial_Search_ID

41591

Preferred_Name

Capsaicin

prefixIRI

ncit:C339

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0006931

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68530

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2198

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http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147626 ODAE LOOM
http://purl.bioontology.org/ontology/UATC/N01BX04 ATC LOOM
http://purl.jp/bio/4/id/200906040660858480 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3374 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.251.355.325.190 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-30379 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D002211 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.160.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019506 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147626 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.760.200 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.166.099 RH-MESH LOOM
http://bmi.utah.edu/ontologies/peontology/C0006931 RAO LOOM
http://stirdf.jst.go.jp/id/200907014064989511 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/M02AB01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/95995002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/CSP/4000-0137 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.326.271.060.222 RH-MESH LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#capsaicin ISO-FOOD LOOM
http://id.loc.gov/authorities/subjects/sh85020016 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RCD/X7956 RCD LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041591 PDQ LOOM
http://purl.bioontology.org/ontology/RXNORM/1992 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002211 RH-MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Capsaicin APAONTO LOOM