loading...| Preferred Name |
Myelodysplastic Syndrome |
|
| Synonyms |
myelodysplasia Myelodysplasia Myelodysplastic Neoplasm Myelodysplastic Syndrome/Neoplasm Oligoblastic Leukemia smoldering leukemia Dysmyelopoietic Syndrome myelodysplastic syndromes Myelodysplastic syndrome Preleukemia Myelodysplastic Syndrome Myelodysplastic Syndromes preleukemia Smoldering Leukemia MDN MDS |
|
| Definitions |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3247 |
|
| ALT_DEFINITION |
A group of diseases in which the bone marrow does not make enough healthy blood cells. A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. A pre-malignant disorder characterized by blood cytopenias and abnormalities in bone marrow morphology. |
|
| code |
C3247 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138190 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103128 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138188 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520 |
|
| Contributing_Source |
Cellosaurus CPTAC CTEP CTRP GDC MedDRA NICHD |
|
| DEFINITION |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| Display_Name |
Myelodysplastic Syndrome |
|
| FULL_SYN |
myelodysplasia Myelodysplasia Myelodysplastic Neoplasm Myelodysplastic Syndrome/Neoplasm Oligoblastic Leukemia smoldering leukemia Dysmyelopoietic Syndrome myelodysplastic syndromes Myelodysplastic syndrome Preleukemia Myelodysplastic Syndrome Myelodysplastic Syndromes preleukemia Smoldering Leukemia MDN MDS |
|
| ICD-O-3_Code |
9989/3 |
|
| Is_Value_For_GDC_Property |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2991 |
|
| label |
Myelodysplastic Syndrome |
|
| Legacy Concept Name |
Myelodysplastic_Syndrome |
|
| Maps_To |
High grade myelodysplastic syndrome lesions Preleukemic syndrome Myelodysplastic syndrome Myelodysplastic syndromes Preleukemia Low grade myelodysplastic syndrome lesions Myelodysplastic syndrome, unspecified Myelodysplastic Syndrome Myelodysplastic Syndromes Other myelodysplastic syndromes |
|
| Neoplastic_Status |
Malignant |
|
| Preferred_Name |
Myelodysplastic Syndrome |
|
| prefixIRI |
Thesaurus:C3247 |
|
| Semantic_Type |
Neoplastic Process |
|
| UMLS_CUI |
C3463824 |
|
| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35501 |