loading...| Preferred Name |
Dicumarol |
|
| Synonyms |
Bishydroxycoumarin 3,3'-Methylenebis(4-hydroxy-2H-1-benzopyran-2-one) DICUMAROL Dicoumarol Dicumarol |
|
| Definitions |
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C310 |
|
| CAS_Registry |
66-76-2 |
|
| CHEBI_ID |
CHEBI:4513 |
|
| Chemical_Formula |
C19H12O6 |
|
| code |
C310 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting. |
|
| FDA_UNII_Code |
7QID3E7BG7 |
|
| FULL_SYN |
Bishydroxycoumarin 3,3'-Methylenebis(4-hydroxy-2H-1-benzopyran-2-one) DICUMAROL Dicoumarol Dicumarol |
|
| label |
Dicumarol |
|
| Legacy Concept Name |
Dicumarol |
|
| NCI_Drug_Dictionary_ID |
40893 |
|
| NSC Number |
41834 |
|
| PDQ_Closed_Trial_Search_ID |
40893 |
|
| PDQ_Open_Trial_Search_ID |
40893 |
|
| Preferred_Name |
Dicumarol |
|
| prefixIRI |
Thesaurus:C310 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0005640 |
|
| subClassOf |