National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Serine

Synonyms

(S)-2-Amino-3-hydroxy-propanoic acid

beta-Hydroxyalanine

2-Amino-3-hydroxypropionic Acid

SERINE

Ser

Serine

l-Serine

Definitions

A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29613

ALT_DEFINITION

Amino acid with side chain -CH2OH.

CAS_Registry

56-45-1

CHEBI_ID

CHEBI:17115

Chemical_Formula

C3H7NO3

code

C29613

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)

Display_Name

Serine

FDA_UNII_Code

452VLY9402

FULL_SYN

(S)-2-Amino-3-hydroxy-propanoic acid

beta-Hydroxyalanine

2-Amino-3-hydroxypropionic Acid

SERINE

Ser

Serine

l-Serine

INFOODS

SER_G

label

Serine

Legacy Concept Name

Serine

NSC Number

118365

Preferred_Name

Serine

prefixIRI

Thesaurus:C29613

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0036720

Unit

g

USDA_ID

518

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29596

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_17822 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 FYPO LOOM
http://purl.obolibrary.org/obo/SO_0001444 SO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 CDNO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.154.800 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D012694 MESH LOOM
http://localhost/plosthes.2017-1#3642 PLOSTHES LOOM
http://id.nlm.nih.gov/mesh/D012694 MDM LOOM
https://www.fns-cloud.eu/foodComponents/FNS_H_0000003431 FNS-H LOOM
http://purl.obolibrary.org/obo/MESH_D012694 BERO LOOM
http://www.co-ode.org/ontologies/galen#Serine GALEN LOOM
http://purl.bioontology.org/ontology/VANDF/4018675 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 PCL LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 MAXO LOOM
https://go.drugbank.com/drugs/DB00133 MDM LOOM
http://stirdf.jst.go.jp/id/200907024557302375 IOBC LOOM
http://purl.obolibrary.org/obo/SO_0001444 NIFSTD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021324 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012694 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146986 NDFRT LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#S AMINO-ACID LOOM
http://purl.bioontology.org/ontology/SNMI/F-64450 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/9671 RXNORM LOOM
http://purl.obolibrary.org/obo/SIBO_0000201 SIBO LOOM
http://purl.org/sig/ont/fma/fma82764 FMA LOOM
http://purl.obolibrary.org/obo/NCIT_C29613 BERO LOOM
http://purl.bioontology.org/ontology/NDDF/006607 NDDF LOOM
http://purl.obolibrary.org/obo/OMIT_0013590 OMIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/14125007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RCD/X807W RCD LOOM
http://purl.jp/bio/10/gmo/GMO_001799 GMO LOOM
http://purl.bioontology.org/ontology/LNC/LP70308-9 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.837 RH-MESH LOOM
http://purl.org/obo/owlapi/fma#FMA_82764 BIOMODELS LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004121 LOINC LOOM
http://purl.jp/bio/4/id/200906074029551723 IOBC LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_17822 NPO LOOM
http://purl.bioontology.org/ontology/CSP/0124-3204 CRISP LOOM
http://doe-generated-ontology.com/OntoAD#C0036720 ONTOAD LOOM
http://www.projecthalo.com/aura#Serine AURA LOOM
http://purl.bioontology.org/ontology/LNC/LP15861-5 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11214 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17822 CHEBI LOOM