National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Tryptophan

Synonyms

TRYPTOPHAN

Tryptophan

(S)-2-Amino-3-(1H-indol-3-yl)-propanoic acid

Trp

Definitions

The least plentiful of all 22 amino acids and an essential amino acid in humans (provided by food), Tryptophan is found in most proteins and a precursor of serotonin. Tryptophan is converted to 5-hydroxy-tryptophan (5-HTP), converted in turn to serotonin, a neurotransmitter essential in regulating appetite, sleep, mood, and pain. Tryptophan is a natural sedative and present in dairy products, meats, brown rice, fish, and soybeans. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29603

ALT_DEFINITION

Amino acid with side chain -CH2C8H6N.

CAS_Registry

73-22-3

CHEBI_ID

CHEBI:16828

Chemical_Formula

C11H12N2O2

code

C29603

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

The least plentiful of all 22 amino acids and an essential amino acid in humans (provided by food), Tryptophan is found in most proteins and a precursor of serotonin. Tryptophan is converted to 5-hydroxy-tryptophan (5-HTP), converted in turn to serotonin, a neurotransmitter essential in regulating appetite, sleep, mood, and pain. Tryptophan is a natural sedative and present in dairy products, meats, brown rice, fish, and soybeans. (NCI04)

Display_Name

Tryptophan

Essential_Amino_Acid

Y

FDA_UNII_Code

8DUH1N11BX

FULL_SYN

TRYPTOPHAN

Tryptophan

(S)-2-Amino-3-(1H-indol-3-yl)-propanoic acid

Trp

INFOODS

TRP_G

label

Tryptophan

Legacy_Concept_Name

Tryptophan

Macronutrient

Y

Nutrient

Y

Preferred_Name

Tryptophan

prefixIRI

ncit:C29603

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0041249

Unit

g

USDA_ID

501

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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http://purl.bioontology.org/ontology/RCD/XM0lC RCD LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#tryptophan ISO-FOOD LOOM
http://purl.obolibrary.org/obo/UPa_UPC00806 UPA LOOM
http://purl.org/obo/owlapi/fma#FMA_82767 BIOMODELS LOOM
http://stirdf.jst.go.jp/id/200907088882463421 IOBC LOOM
http://scai.fraunhofer.de/MSOntology#Tryptophan MSO LOOM
http://purl.bioontology.org/ontology/LNC/LP15931-6 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12617 OCHV LOOM
http://purl.jp/bio/10/gmo/GMO_001215 GMO LOOM
http://d-nb.info/gnd/4186362-8 FAST-TOPICAL LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014364 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146988 NDFRT LOOM
http://purl.org/sig/ont/fma/fma82767 FMA LOOM
http://purl.jp/bio/4/id/200906010284117460 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 BIPON LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 PECO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27897 FYPO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.072.050.850 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Tryptophan GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/54821000 SNOMEDCT LOOM
http://localhost/plosthes.2017-1#522 PLOSTHES LOOM
http://purl.bioontology.org/ontology/UATC/N06AX02 ATC LOOM
http://www.projecthalo.com/aura#Tryptophan AURA LOOM
http://id.loc.gov/authorities/subjects/sh86000850 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/CSP/0777-8222 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004124 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/10898 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.142.875 RH-MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Tryptophan APAONTO LOOM
http://purl.bioontology.org/ontology/SNMI/F-64480 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/001438 NDDF LOOM
http://purl.bioontology.org/ontology/MESH/D014364 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4018677 VANDF LOOM
http://purl.obolibrary.org/obo/SO_0001440 SO LOOM
http://purl.obolibrary.org/obo/SO_0001440 ORTH LOOM
http://purl.obolibrary.org/obo/SO_0001440 NIFSTD LOOM
http://www.co-ode.org/ontologies/amino-acid/2006/05/18/amino-acid.owl#W AMINO-ACID LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_27897 NPO LOOM