National Cancer Institute Thesaurus

Last uploaded: July 29, 2019
Preferred Name

Histidine

Synonyms

His

Histidine

l-Histidine

(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid

HISTIDINE

Definitions

A semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29597

ALT_DEFINITION

Amino acid with side chain -CH2-C3H3N2.

CAS_Registry

71-00-1

CHEBI_ID

CHEBI:15971

Chemical_Formula

C6H9N3O2

code

C29597

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

A semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. (NCI04)

Display_Name

Histidine

Essential_Amino_Acid

Y

FDA_UNII_Code

4QD397987E

FULL_SYN

His

Histidine

l-Histidine

(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid

HISTIDINE

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87704

INFOODS

HISTN_G

label

Histidine

Legacy_Concept_Name

Histidine

Macronutrient

Y

NSC_Code

137773

Nutrient

Y

Preferred_Name

Histidine

prefixIRI

ncit:C29597

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0019602

Unit

g

USDA_ID

512

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

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http://purl.obolibrary.org/obo/CHEBI_27570 FYPO LOOM
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http://purl.org/sig/ont/fma/fma82755 FMA LOOM
http://purl.org/sig/ont/fma/fma82755 FMA LOOM
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http://www.projecthalo.com/aura#Histidine AURA LOOM
http://localhost/plosthes.2017-1#1655 PLOSTHES LOOM
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