National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Tioconazole

Synonyms

Tioconazole

TIOCONAZOLE

Definitions

A synthetic imidazole derivative, fungicidal Terconazole inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Tioconazole is active against pathogenic Candida. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29500

CAS_Registry

65899-73-2

Chemical_Formula

C16H13Cl3N2OS

code

C29500

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic imidazole derivative, fungicidal Terconazole inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Tioconazole is active against pathogenic Candida. (NCI04)

FDA_UNII_Code

S57Y5X1117

FULL_SYN

Tioconazole

TIOCONAZOLE

label

Tioconazole

Legacy Concept Name

Tioconazole

Preferred_Name

Tioconazole

prefixIRI

Thesaurus:C29500

Semantic_Type

Pharmacologic Substance

Antibiotic

UMLS_CUI

C0076705

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C514

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