loading...| Preferred Name |
Bacitracin |
|
| Synonyms |
BACITRACIN Bacitracin |
|
| Definitions |
A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C295 |
|
| CAS_Registry |
1405-87-4 |
|
| CHEBI_ID |
CHEBI:28669 |
|
| code |
C295 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth. |
|
| FDA_UNII_Code |
58H6RWO52I |
|
| FULL_SYN |
BACITRACIN Bacitracin |
|
| Has_Salt_Form | ||
| label |
Bacitracin |
|
| Legacy Concept Name |
Bacitracin |
|
| NCI_Drug_Dictionary_ID |
42858 |
|
| NSC Number |
45737 |
|
| PDQ_Closed_Trial_Search_ID |
42858 |
|
| PDQ_Open_Trial_Search_ID |
42858 |
|
| Preferred_Name |
Bacitracin |
|
| prefixIRI |
Thesaurus:C295 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0004599 |
|
| subClassOf |