Preferred Name |
Ranitidine |
|
Synonyms |
N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine RANITIDINE Ranitidine |
|
Definitions |
A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29412 |
|
CAS_Registry |
66357-35-5 |
|
CHEBI_ID |
CHEBI:8776 |
|
Chemical_Formula |
C13H22N4O3S |
|
code |
C29412 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA HemOnc |
|
DEFINITION |
A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked. |
|
FDA_UNII_Code |
884KT10YB7 |
|
FULL_SYN |
N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine RANITIDINE Ranitidine |
|
Has_Salt_Form | ||
label |
Ranitidine |
|
Legacy Concept Name |
Ranitidine |
|
Preferred_Name |
Ranitidine |
|
prefixIRI |
Thesaurus:C29412 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0034665 |
|
subClassOf |