National Cancer Institute Thesaurus

Last uploaded: March 26, 2019
Preferred Name

Propofol

Synonyms

Propofol

PROPOFOL

Diprivan

Definitions

A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29384

CAS_Registry

2078-54-8

CHEBI_ID

CHEBI:44915

Chemical_Formula

C12H18O

code

C29384

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

FDA

DEFINITION

A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.

Display_Name

Propofol

FDA_UNII_Code

YI7VU623SF

FULL_SYN

Propofol

PROPOFOL

Diprivan

label

Propofol

Legacy_Concept_Name

Propofol

NSC_Code

5105

PDQ_Closed_Trial_Search_ID

461189

PDQ_Open_Trial_Search_ID

461189

Preferred_Name

Propofol

prefixIRI

ncit:C29384

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0033487

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29756

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http://www.drugbank.ca/drugs/DB00818 FTC LOOM
http://purl.bioontology.org/ontology/NDDF/003528 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.773 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/74674007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP31828-4 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147620 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D015742 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015742 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Propofol GALEN LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000461189 PDQ LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147620 ODAE LOOM
http://purl.bioontology.org/ontology/UATC/N01AX10 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/8782 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019500 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015674 LOINC LOOM
http://stirdf.jst.go.jp/id/200907054445320229 IOBC LOOM
http://purl.jp/bio/4/id/200906011945928954 IOBC LOOM
http://purl.jp/bio/4/id/200906011945928954 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387423006 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-6A156 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/o15.. RCD LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Propofol APAONTO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 OBIB LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_44915 NIFSTD LOOM