National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Permethrin

Synonyms

(+/-)-3-Phenoxybenzyl 3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate

M-Phenoxybenzyl (+/-)-3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate

Cyclopropanecarboxylic Acid, 3-(2,2-Dichloroethenyl)-2,2-Dimethyl-, (3-Phenoxyphenyl)Methyl Ester

Elimite

Nix

PERMETHRIN

Permethrin

Definitions

A synthetic pyrethroid and neurotoxin. Permethrin affects the neuronal membrane by blocking the movement of sodium ions from outside to inside the neuronal cell membrane thereby disrupting the sodium channel current that regulates the polarization of the membrane. This leads to delayed repolarization and subsequent paralysis of the nervous system. Permethrin is used to eradicate parasites such as head lice, ticks and scabies from humans and animals.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29354

CAS_Registry

52645-53-1

CHEBI_ID

CHEBI:34911

Chemical_Formula

C21H20Cl2O3

code

C29354

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic pyrethroid and neurotoxin. Permethrin affects the neuronal membrane by blocking the movement of sodium ions from outside to inside the neuronal cell membrane thereby disrupting the sodium channel current that regulates the polarization of the membrane. This leads to delayed repolarization and subsequent paralysis of the nervous system. Permethrin is used to eradicate parasites such as head lice, ticks and scabies from humans and animals.

FDA_UNII_Code

509F88P9SZ

FULL_SYN

(+/-)-3-Phenoxybenzyl 3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate

M-Phenoxybenzyl (+/-)-3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate

Cyclopropanecarboxylic Acid, 3-(2,2-Dichloroethenyl)-2,2-Dimethyl-, (3-Phenoxyphenyl)Methyl Ester

Elimite

Nix

PERMETHRIN

Permethrin

label

Permethrin

Legacy Concept Name

Permethrin

Preferred_Name

Permethrin

prefixIRI

Thesaurus:C29354

Semantic_Type

Organic Chemical

Pharmacologic Substance

Hazardous or Poisonous Substance

UMLS_CUI

C0070455

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29727

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http://purl.obolibrary.org/obo/CHEBI_34911 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 CHEBI LOOM
http://purl.bioontology.org/ontology/MESH/D026023 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14599 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/C-23245 SNMI LOOM
http://purl.jp/bio/4/id/200906006025231257 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D026023 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017101 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/33199 RXNORM LOOM
http://purl.bioontology.org/ontology/RCD/mg8.. RCD LOOM
http://purl.obolibrary.org/obo/MESH_D026023 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0070455 OCHV LOOM
http://stirdf.jst.go.jp/id/200907045744051979 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0021197 OMIT LOOM
http://www.co-ode.org/ontologies/galen#Permethrin GALEN LOOM
http://www.drugbank.ca/drugs/DB04930 FTC LOOM
http://purl.obolibrary.org/obo/MIRO_10000144 MIRO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147078 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 EUPATH LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 IDOMAL LOOM
http://purl.obolibrary.org/obo/CHEBI_34911 IDODEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.575.812.636 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/410457007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4018775 VANDF LOOM
https://go.drugbank.com/drugs/DB04930 MDM LOOM
http://purl.bioontology.org/ontology/ATC/P03AC04 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C29354 BERO LOOM