National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Azlocillin

Synonyms

AZLOCILLIN

Azlin

Azlocillin

Definitions

A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C293

CAS_Registry

37091-66-0

CHEBI_ID

CHEBI:2956

Chemical_Formula

C20H23N5O6S

code

C293

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.

FDA_UNII_Code

HUM6H389W0

FULL_SYN

AZLOCILLIN

Azlin

Azlocillin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65243

label

Azlocillin

Legacy Concept Name

Azlocillin

NCI_Drug_Dictionary_ID

39160

PDQ_Closed_Trial_Search_ID

39160

PDQ_Open_Trial_Search_ID

39160

Preferred_Name

Azlocillin

prefixIRI

Thesaurus:C293

Semantic_Type

Organic Chemical

Pharmacologic Substance

Antibiotic

UMLS_CUI

C0004499

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

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Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.108.750.750.050.075 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/J01CA09 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015927 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/1266 RXNORM LOOM
http://purl.bioontology.org/ontology/SNMI/C-54B10 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.750.750.050.075 RH-MESH LOOM
https://go.drugbank.com/drugs/DB01061 MDM LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_2956 MCO LOOM
http://stirdf.jst.go.jp/id/200907030276200689 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/004836 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.737.750.050.075 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/e41.. RCD LOOM
http://purl.obolibrary.org/obo/NCIT_C293 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0002767 OMIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039160 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4019621 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006797 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP16040-5 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D001390 MESH LOOM
http://purl.jp/bio/4/id/200906011882921075 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147715 NDFRT LOOM
http://purl.obolibrary.org/obo/ARO_3000638 ARO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387308000 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.750.750.050.075 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.260.825.750.050.075 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D001390 BERO LOOM
http://www.co-ode.org/ontologies/galen#Azlocillin GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D001390 RH-MESH LOOM