National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Nizatidine

Synonyms

Axid

NIZATIDINE

Nizatidine

Definitions

A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29295

CAS_Registry

76963-41-2

Chemical_Formula

C12H21N5O2S2

code

C29295

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli.

FDA_UNII_Code

P41PML4GHR

FULL_SYN

Axid

NIZATIDINE

Nizatidine

label

Nizatidine

Legacy Concept Name

Nizatidine

Preferred_Name

Nizatidine

prefixIRI

Thesaurus:C29295

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0085154

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29702

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http://purl.obolibrary.org/obo/CHEBI_7601 CHEBI LOOM
http://purl.jp/bio/4/id/200906063112589293 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0085154 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15465 OCHV LOOM
http://purl.obolibrary.org/obo/dinto_DB00585 DINTO LOOM
http://purl.obolibrary.org/obo/NCIT_C29295 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.708.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP19170-7 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016567 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00585 FTC LOOM
http://purl.bioontology.org/ontology/MESH/D016567 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/42319 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907099859668735 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007483 LOINC LOOM
http://purl.obolibrary.org/obo/OMIT_0017042 OMIT LOOM
http://www.co-ode.org/ontologies/galen#Nizatidine GALEN LOOM
http://purl.obolibrary.org/obo/MESH_D016567 BERO LOOM
http://purl.bioontology.org/ontology/RCD/a69.. RCD LOOM
http://purl.obolibrary.org/obo/CHEBI_7601 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7601 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_7601 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7601 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.675.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386887009 SNOMEDCT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017482 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147517 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4019342 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/A02BA04 ATC LOOM
https://go.drugbank.com/drugs/DB00585 MDM LOOM