Preferred Name |
Nizatidine |
|
Synonyms |
Axid NIZATIDINE Nizatidine |
|
Definitions |
A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29295 |
|
CAS_Registry |
76963-41-2 |
|
Chemical_Formula |
C12H21N5O2S2 |
|
code |
C29295 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli. |
|
FDA_UNII_Code |
P41PML4GHR |
|
FULL_SYN |
Axid NIZATIDINE Nizatidine |
|
label |
Nizatidine |
|
Legacy Concept Name |
Nizatidine |
|
Preferred_Name |
Nizatidine |
|
prefixIRI |
Thesaurus:C29295 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0085154 |
|
subClassOf |