National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Methocarbamol

Synonyms

METHOCARBAMOL

Methocarbamol

Robaxin

Definitions

A carbamate with centrally acting muscle relaxant properties. Though the exact mechanism of action of methocarbamol was not established, it's postulated to be via a mechanism similar of carbamate, inhibition of acetylcholinesterase at synapses in the autonomic nervous system, neuromuscular junction, and central nervous system. Methocarbamol has no direct effect on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29252

CAS_Registry

532-03-6

Chemical_Formula

C11H15NO5

code

C29252

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A carbamate with centrally acting muscle relaxant properties. Though the exact mechanism of action of methocarbamol was not established, it's postulated to be via a mechanism similar of carbamate, inhibition of acetylcholinesterase at synapses in the autonomic nervous system, neuromuscular junction, and central nervous system. Methocarbamol has no direct effect on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.

FDA_UNII_Code

125OD7737X

FULL_SYN

METHOCARBAMOL

Methocarbamol

Robaxin

label

Methocarbamol

Legacy Concept Name

Methocarbamol

NSC Number

170960

Preferred_Name

Methocarbamol

prefixIRI

Thesaurus:C29252

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0025659

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29696

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http://purl.obolibrary.org/obo/CHEBI_6832 CHEBI LOOM
http://purl.bioontology.org/ontology/SNMI/C-687F0 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D008721 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025659 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.251.515 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6832 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6832 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6832 DRON LOOM
http://purl.bioontology.org/ontology/LNC/LP16197-3 LOINC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016372 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.654.453.400.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0009780 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.251.583.577 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C29252 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008721 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017879 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Methocarbamol GALEN LOOM
http://stirdf.jst.go.jp/id/200907002980793683 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146232 NDFRT LOOM
http://purl.bioontology.org/ontology/NDDF/001669 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387486000 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.355.726.453.400.500 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00423 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8040 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_77498 FIDEO LOOM
http://purl.obolibrary.org/obo/MESH_D008721 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007392 LOINC LOOM
http://www.drugbank.ca/drugs/DB00423 FTC LOOM
http://purl.jp/bio/4/id/200906033073789909 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.355.601.536.400.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/6845 RXNORM LOOM
http://purl.obolibrary.org/obo/dinto_DB00423 DINTO LOOM
http://purl.bioontology.org/ontology/ATC/M03BA03 ATC LOOM
http://purl.bioontology.org/ontology/RCD/j85.. RCD LOOM