National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Guaifenesin

Synonyms

GUAIFENESIN

3-(o-Methoxyphenoxy)-1,2-propanediol

Guaifenesin

Glyceryl Guaiacolate

Humibid

Mucinex

Definitions

A glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29081

CAS_Registry

93-14-1

CHEBI_ID

CHEBI:5551

Chemical_Formula

C10H14O4

code

C29081

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.

FDA_UNII_Code

495W7451VQ

FULL_SYN

GUAIFENESIN

3-(o-Methoxyphenoxy)-1,2-propanediol

Guaifenesin

Glyceryl Guaiacolate

Humibid

Mucinex

label

Guaifenesin

Legacy Concept Name

Guaifenesin

NSC Number

62112

Preferred_Name

Guaifenesin

prefixIRI

Thesaurus:C29081

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0018305

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29767

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Delete Mapping To Ontology Source
http://www.phoc.org.cn/pmo/class/PMO_00016612 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/VANDF/4018147 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0018305 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0007321 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060484 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/5032 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.166.453.400 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.355.601.536.400 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/R05CA03 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.355.726.453.400 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.654.453.400 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-88310 SNMI LOOM
http://purl.obolibrary.org/obo/MESH_D006140 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146484 NDFRT LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00889 COID LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D006140 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5726 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_5551 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_5551 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_5551 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_5551 CHEBI LOOM
http://purl.jp/bio/4/id/200906040706121739 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/000724 NDDF LOOM
http://stirdf.jst.go.jp/id/200907096042569680 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/87174009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP18968-5 LOINC LOOM
https://go.drugbank.com/drugs/DB00874 MDM LOOM
http://purl.obolibrary.org/obo/dinto_DB00874 DINTO LOOM
http://purl.obolibrary.org/obo/NCIT_C29081 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D006140 MESH LOOM