Preferred Name |
Famotidine |
|
Synonyms |
FAMOTIDINE Famotidine Pepcid Pepcid AC |
|
Definitions |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29045 |
|
CAS_Registry |
76824-35-6 |
|
CHEBI_ID |
CHEBI:4975 |
|
Chemical_Formula |
C8H15N7O2S3 |
|
code |
C29045 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
Contributing_Source |
CTRP FDA HemOnc |
|
DEFINITION |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. |
|
Display_Name |
Famotidine |
|
FDA_UNII_Code |
5QZO15J2Z8 |
|
FULL_SYN |
FAMOTIDINE Famotidine Pepcid Pepcid AC |
|
Has_Target | ||
label |
Famotidine |
|
Legacy Concept Name |
Famotidine |
|
NCI_Drug_Dictionary_ID |
574268 |
|
PDQ_Closed_Trial_Search_ID |
574268 |
|
PDQ_Open_Trial_Search_ID |
574268 |
|
Preferred_Name |
Famotidine |
|
prefixIRI |
Thesaurus:C29045 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0015620 |
|
subClassOf |