Preferred Name |
Famciclovir |
|
Synonyms |
2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol Diacetate (ester) Famciclovir FAMCICLOVIR BRL 42810 BRL-42810 Famvir |
|
Definitions |
A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 |
|
CAS_Registry |
104227-87-4 |
|
CHEBI_ID |
CHEBI:4974 |
|
Chemical_Formula |
C14H19N5O4 |
|
code |
C29044 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA HemOnc |
|
DEFINITION |
A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04) |
|
FDA_UNII_Code |
QIC03ANI02 |
|
FULL_SYN |
2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol Diacetate (ester) Famciclovir FAMCICLOVIR BRL 42810 BRL-42810 Famvir |
|
label |
Famciclovir |
|
Legacy Concept Name |
Famciclovir |
|
Preferred_Name |
Famciclovir |
|
prefixIRI |
Thesaurus:C29044 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0209227 |
|
subClassOf |