National Cancer Institute Thesaurus

Last uploaded: December 30, 2019
Preferred Name

Doxycycline Calcium

Synonyms

Doxycycline Calcium

Vibramycin

DOXYCYCLINE CALCIUM

Definitions

The calcium salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. (NCI)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29008

CAS_Registry

94088-85-4

Chemical_Formula

C22H24N2O8.2Ca

code

C29008

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The calcium salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. (NCI)

FDA_UNII_Code

8ZL07I20SB

FULL_SYN

Doxycycline Calcium

Vibramycin

DOXYCYCLINE CALCIUM

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C457

label

Doxycycline Calcium

Legacy_Concept_Name

Doxycycline_Calcium

Preferred_Name

Doxycycline Calcium

prefixIRI

ncit:C29008

Semantic_Type

Organic Chemical

Antibiotic

UMLS_CUI

C0282155

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1595

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http://purl.bioontology.org/ontology/NDDF/002749 NDDF LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042494 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4017740 VANDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-55021 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/63559007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/82012 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146107 NDFRT LOOM