Preferred Name |
Doxycycline Hyclate |
|
Synonyms |
doxycycline hyclate Doxycycline Hyclate DOXYCYCLINE HYCLATE Doryx |
|
Definitions |
The hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29007 |
|
ALT_DEFINITION |
A drug used to treat many types of bacterial infections. It stops the growth of bacteria by keeping them from making proteins. It is a type of antibiotic. |
|
CAS_Registry |
24390-14-5 |
|
CHEBI_ID |
CHEBI:34730 |
|
Chemical_Formula |
2C22H24N2O8.C2H6O.2HCl.H2O |
|
code |
C29007 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
The hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. |
|
Display_Name |
Doxycycline Hyclate |
|
FDA_UNII_Code |
19XTS3T51U |
|
FULL_SYN |
doxycycline hyclate Doxycycline Hyclate DOXYCYCLINE HYCLATE Doryx |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Doxycycline Hyclate |
|
Legacy Concept Name |
Doxycline_Hyclate |
|
NCI_Drug_Dictionary_ID |
669084 |
|
PDQ_Closed_Trial_Search_ID |
669084 |
|
PDQ_Open_Trial_Search_ID |
669084 |
|
Preferred_Name |
Doxycycline Hyclate |
|
prefixIRI |
Thesaurus:C29007 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
UMLS_CUI |
C0058731 |
|
subClassOf |