loading...| Preferred Name |
Clozapine |
|
| Synonyms |
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine CLOZAPINE Clozapine |
|
| Definitions |
A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28936 |
|
| CAS_Registry |
5786-21-0 |
|
| CHEBI_ID |
CHEBI:3766 |
|
| Chemical_Formula |
C18H19ClN4 |
|
| code |
C28936 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). (NCI04) |
|
| FDA_UNII_Code |
J60AR2IKIC |
|
| FULL_SYN |
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine CLOZAPINE Clozapine |
|
| label |
Clozapine |
|
| Legacy Concept Name |
Clozapine |
|
| NCI_Drug_Dictionary_ID |
800675 |
|
| PDQ_Closed_Trial_Search_ID |
800675 |
|
| PDQ_Open_Trial_Search_ID |
800675 |
|
| Preferred_Name |
Clozapine |
|
| prefixIRI |
Thesaurus:C28936 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0009079 |
|
| subClassOf |