National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Cholestyramine

Synonyms

CHOLESTYRAMINE

Questran Light

Colestyramine

Cholestyramine

Cholybar

Questran

Duolite AP143 Resin

Definitions

An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28929

CAS_Registry

11041-12-6

Chemical_Formula

(C12H18ClN)n.(C10H10)n

code

C28929

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels.

FDA_UNII_Code

4B33BGI082

FULL_SYN

CHOLESTYRAMINE

Questran Light

Colestyramine

Cholestyramine

Cholybar

Questran

Duolite AP143 Resin

label

Cholestyramine

Legacy_Concept_Name

Cholestyramine

NSC_Code

177361

Preferred_Name

Cholestyramine

prefixIRI

ncit:C28929

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0008402

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98148

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http://purl.bioontology.org/ontology/CSP/0157-1427 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008402 OCHV LOOM
http://purl.obolibrary.org/obo/dinto_DB01432 DINTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387408001 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2887 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147114 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4018811 VANDF LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147114 OCVDAE LOOM
http://purl.bioontology.org/ontology/SNMI/C-80620 SNMI LOOM
http://purl.bioontology.org/ontology/NDDF/001216 NDDF LOOM
http://www.co-ode.org/ontologies/galen#Cholestyramine GALEN LOOM