loading...| Preferred Name |
Cefprozil |
|
| Synonyms |
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, (6R,7R)- BMY 28100 CEFPROZIL Cefprozil |
|
| Definitions |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28917 |
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| CAS_Registry |
121123-17-9 |
|
| code |
C28917 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation. |
|
| FDA_UNII_Code |
4W0459ZA4V |
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| FULL_SYN |
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, (6R,7R)- BMY 28100 CEFPROZIL Cefprozil |
|
| label |
Cefprozil |
|
| Legacy Concept Name |
Cefprozil |
|
| Preferred_Name |
Cefprozil |
|
| prefixIRI |
Thesaurus:C28917 |
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| Semantic_Type |
Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0053882 |
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| subClassOf |