loading...| Preferred Name |
Cefdinir |
|
| Synonyms |
CEFDINIR Cefdinir |
|
| Definitions |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28914 |
|
| CAS_Registry |
91832-40-5 |
|
| CHEBI_ID |
CHEBI:3485 |
|
| Chemical_Formula |
C14H13N5O5S2 |
|
| code |
C28914 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation. |
|
| FDA_UNII_Code |
CI0FAO63WC |
|
| FULL_SYN |
CEFDINIR Cefdinir |
|
| label |
Cefdinir |
|
| Legacy Concept Name |
Cefdinir |
|
| Preferred_Name |
Cefdinir |
|
| prefixIRI |
Thesaurus:C28914 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0060405 |
|
| subClassOf |