National Cancer Institute Thesaurus

Last uploaded: June 25, 2019
Preferred Name

Bumetanide

Synonyms

Bumetanide

BUMETANIDE

Bumex

Definitions

A potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28875

CAS_Registry

28395-03-1

CHEBI_ID

CHEBI:3213

Chemical_Formula

C17H20N2O5S

code

C28875

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

FDA

DEFINITION

A potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.

Display_Name

Bumetanide

FDA_UNII_Code

0Y2S3XUQ5H

FULL_SYN

Bumetanide

BUMETANIDE

Bumex

label

Bumetanide

Legacy_Concept_Name

Bumetanide

PDQ_Closed_Trial_Search_ID

788832

PDQ_Open_Trial_Search_ID

788832

Preferred_Name

Bumetanide

prefixIRI

ncit:C28875

Semantic_Type

Organic Chemical

UMLS_CUI

C0701009

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49184

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/RCD/b32.. RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4017794 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387498005 SNOMEDCT LOOM
http://stirdf.jst.go.jp/id/200907027423743900 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006833 LOINC LOOM
http://purl.jp/bio/4/id/200906082003803921 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002312 NDDF LOOM
http://purl.bioontology.org/ontology/CSP/2840-3310 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP16052-0 LOINC LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#bumetanide FASTO LOOM
http://www.drugbank.ca/drugs/DB00887 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.127.020.452.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005287 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005619 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005619 DMTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146155 NDFRT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005291 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005291 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002034 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Bumetanide GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-72020 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3213 CHEBI LOOM
http://bmi.utah.edu/ontologies/hfontology/C0006376 HFO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.884.150 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.100.050.300.200 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1808 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/C03CA02 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D002034 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.700.150 RH-MESH LOOM