loading...| Preferred Name |
Atovaquone |
|
| Synonyms |
566C80 ATOVAQUONE Atovaquone BW-566C BW-A566C Mepron |
|
| Definitions |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28838 |
|
| CAS_Registry |
95233-18-4 |
|
| CHEBI_ID |
CHEBI:575568 |
|
| Chemical_Formula |
C22H19ClO3 |
|
| code |
C28838 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 |
|
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death. |
|
| FDA_UNII_Code |
Y883P1Z2LT |
|
| FULL_SYN |
566C80 ATOVAQUONE Atovaquone BW-566C BW-A566C Mepron |
|
| label |
Atovaquone |
|
| Legacy Concept Name |
Atovoquone |
|
| NCI_Drug_Dictionary_ID |
797848 |
|
| PDQ_Closed_Trial_Search_ID |
797848 |
|
| PDQ_Open_Trial_Search_ID |
797848 |
|
| Preferred_Name |
Atovaquone |
|
| prefixIRI |
Thesaurus:C28838 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0165603 |
|
| subClassOf |