loading...| Preferred Name |
Astemizole |
|
| Synonyms |
1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)eth l)-4-piperidinyl)- ASTEMIZOLE Astemizole Hismanal Paralergin R 42512 R 43,512 Retolen |
|
| Definitions |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28834 |
|
| CAS_Registry |
68844-77-9 |
|
| CHEBI_ID |
CHEBI:2896 |
|
| Chemical_Formula |
C28H31FN4O |
|
| code |
C28834 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04) |
|
| FDA_UNII_Code |
7HU6337315 |
|
| FULL_SYN |
1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)eth l)-4-piperidinyl)- ASTEMIZOLE Astemizole Hismanal Paralergin R 42512 R 43,512 Retolen |
|
| label |
Astemizole |
|
| Legacy Concept Name |
Astemizole |
|
| Preferred_Name |
Astemizole |
|
| prefixIRI |
Thesaurus:C28834 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0699606 |
|
| subClassOf |