National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Aspirin

Synonyms

2-(Acetyloxy)benzoic Acid

Acetylsalicylic acid

Acetylsalicylic Acid

ASA

ASPIRIN

Aspergum

Aspirin

Ecotrin

Empirin

Entericin

Extren

Measurin

aspirin

Definitions

An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C287

Accepted_Therapeutic_Use_For

Mild to moderate pain; fever; prevention of arterial and venous thrombosis

ALT_DEFINITION

Acetylsalicylic acid decreases synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

A drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention.

CAS_Registry

50-78-2

CHEBI_ID

CHEBI:15365

Chemical_Formula

C9H8O4

code

C287

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191405

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

ACC/AHA

CTRP

FDA

GDC

HemOnc

DEFINITION

An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

Display_Name

Aspirin

FDA_UNII_Code

R16CO5Y76E

FULL_SYN

2-(Acetyloxy)benzoic Acid

Acetylsalicylic acid

Acetylsalicylic Acid

ASA

ASPIRIN

Aspergum

Aspirin

Ecotrin

Empirin

Entericin

Extren

Measurin

aspirin

Has_ACC-AHA_SARS2_Authorized_Value

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49488

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49487

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83539

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C200709

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C200710

Has_Target

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17984

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C202155

label

Aspirin

Legacy Concept Name

Acetylsalicylic_Acid

Maps_To

Aspirin

NCI_Drug_Dictionary_ID

39152

NSC Number

406186

PDQ_Closed_Trial_Search_ID

39152

PDQ_Open_Trial_Search_ID

39152

Preferred_Name

Aspirin

prefixIRI

Thesaurus:C287

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0004057

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1323

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Delete Mapping To Ontology Source
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_d4b9fd6f_50e6_4e0e_bc7f_50cc56be17fd STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_d4b9fd6f_50e6_4e0e_bc7f_50cc56be17fd CVAO LOOM
http://www.stanford.edu/~coulet/phare.owl#Aspirin PHARE LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01068 MIO LOOM
http://www.gamuts.net/entity#aspirin GAMUTS LOOM
http://purl.bioontology.org/ontology/NDDF/001587 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1530 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/1191 RXNORM LOOM
http://www.semanticweb.org/ontologies/2010/10/BPO.owl#aspirin BHO LOOM
http://purl.obolibrary.org/obo/NCIT_C287 BERO LOOM
http://www.pepathway.org/peo/1.2#Aspirin PE-O LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145918 NDFRT LOOM
http://purl.obolibrary.org/obo/OMIT_0002626 OMIT LOOM
http://purl.obolibrary.org/obo/MESH_D001241 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D001241 MESH LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571352688529240103 ACVD_ONTOLOGY LOOM
http://bmi.utah.edu/ontologies/peontology/C0004057 PE LOOM
http://www.semanticweb.org/emif/ontologies/2015/AD/Rs2wXLfJwhy6QfA5ShGSqy EMIF-AD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D001241 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0004057 OCHV LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#aspirin SDO LOOM
http://stirdf.jst.go.jp/id/200907003176696035 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/2270-2387 CRISP LOOM
http://purl.jp/bio/4/id/200906069238964888 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Aspirin GALEN LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Aspirin PCAO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016861 PMAPP-PMO LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00349 COID LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387458008 SNOMEDCT LOOM
http://doe-generated-ontology.com/OntoAD#C0004057 ONTOAD LOOM
http://purl.bioontology.org/ontology/LNC/LA26702-3 LOINC LOOM
http://www.owl-ontologies.com/OntologyXCT.owl#Aspirin CTX LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000145918 OCVDAE LOOM
http://purl.bioontology.org/ontology/RCD/x02LX RCD LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Aspirin APAONTO LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Aspirin STMSO LOOM
http://bmi.utah.edu/ontologies/hfontology/C0004057 HFO LOOM
http://purl.bioontology.org/ontology/VANDF/4017536 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.657.410.595.176 RH-MESH LOOM