National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fluoride Ion

Synonyms

FLUORIDE ION

Fluoride Ion

F-

Fluoride

Fluorine-

fluoride

Definitions

Considered a trace element, fluoride is any combination of elements containing the fluorine atom in the -1 oxidation state (fluoride ion). Due to its reactivity, fluorine is found in nature as fluorine compounds or fluorides. Fluoride inhibits various enzyme systems, erythrocyte glycolysis and binds Ca++, causing anticoagulation and other toxic effects. In addition, fluoride is a mitogen for osteoblasts and stimulates bone formation. (NCI)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28149

ALT_DEFINITION

Fluorine ion requiring removal of one electron to return to its elemental state.

A form of the element fluorine that helps prevent tooth decay. Fluoride may be naturally present in drinking water or may be added to it. Fluoride may also be put directly on the teeth, as a gel, toothpaste, or a rinse.

CAS_Registry

16984-48-8

CHEBI_ID

CHEBI:17051

Chemical_Formula

F

code

C28149

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

Considered a trace element, fluoride is any combination of elements containing the fluorine atom in the -1 oxidation state (fluoride ion). Due to its reactivity, fluorine is found in nature as fluorine compounds or fluorides. Fluoride inhibits various enzyme systems, erythrocyte glycolysis and binds Ca++, causing anticoagulation and other toxic effects. In addition, fluoride is a mitogen for osteoblasts and stimulates bone formation. (NCI)

FDA_UNII_Code

Q80VPU408O

FULL_SYN

FLUORIDE ION

Fluoride Ion

F-

Fluoride

Fluorine-

fluoride

label

Fluoride Ion

Legacy Concept Name

Fluoride

Preferred_Name

Fluoride Ion

prefixIRI

Thesaurus:C28149

Semantic_Type

Element, Ion, or Isotope

UMLS_CUI

C0677517

Unit

mcg

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68252

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