National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Creutzfeldt-Jakob Disease

Synonyms

Creutzfeldt-Jacob Disease

Classic Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease

CJD

Definitions

A rare transmittable degenerative disorder of the brain caused by prions. Morphologically it is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Signs and symptoms include sleep disturbances, personality changes, aphasia, ataxia, muscle atrophy and weakness, visual loss, and myoclonus. It usually leads to death within a year from the onset of the disease.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26802

ALT_DEFINITION

A prion disease of humans that is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Three recognized forms are sporadic, familial, and iatrogenic. The iatrogenic form occurs through direct contact with human tissue, a product derived from human tissue, or contaminated medical equipment.

code

C26802

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128453

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

Contributing_Source

NICHD

DEFINITION

A rare transmittable degenerative disorder of the brain caused by prions. Morphologically it is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Signs and symptoms include sleep disturbances, personality changes, aphasia, ataxia, muscle atrophy and weakness, visual loss, and myoclonus. It usually leads to death within a year from the onset of the disease.

FULL_SYN

Creutzfeldt-Jacob Disease

Classic Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease

CJD

label

Creutzfeldt-Jakob Disease

Legacy Concept Name

Creutzfeldt-Jacob_Disease

Preferred_Name

Creutzfeldt-Jakob Disease

prefixIRI

Thesaurus:C26802

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0022336

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128346

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