National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

ACE Inhibitor

Synonyms

angiotensin-converting enzyme inhibitor

ACE Inhibitor

Angiotensin-Converting Enzyme Inhibitor

ACE inhibitor

Definitions

Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247

Accepted_Therapeutic_Use_For

Hypertension

ALT_DEFINITION

A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent.

A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension.

CHEBI_ID

CHEBI:35457

code

C247

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

Contributing_Source

NICHD

DEFINITION

Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.

FULL_SYN

angiotensin-converting enzyme inhibitor

ACE Inhibitor

Angiotensin-Converting Enzyme Inhibitor

ACE inhibitor

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

ACE Inhibitor

Legacy_Concept_Name

ACE_Inhibitor

NICHD_Hierarchy_Term

ACE Inhibitor

Preferred_Name

ACE Inhibitor

prefixIRI

ncit:C247

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0003015

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C270

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/CSP/1037-0850 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP213629-1 LOINC LOOM
http://www.pepathway.org/peo/1.2#ACE_inhibitor PE-O LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247 ROO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247 ROO SAME_URI
http://radlex.org/RID/RID43373 RADLEX LOOM
http://scai.fraunhofer.de/AlzheimerOntology#ACE_inhibitor ADO LOOM