National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

ACE Inhibitor

Synonyms

ACE Inhibitor

Angiotensin-Converting Enzyme Inhibitor

angiotensin-converting enzyme inhibitor

Angiotensin-converting enzyme (ACE) inhibitor medication

ACE inhibitor

ACE-inhibitor

Definitions

Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247

Accepted_Therapeutic_Use_For

Hypertension

ALT_DEFINITION

A medication that inhibits ACE, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.

A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent.

A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension.

CHEBI_ID

CHEBI:35457

code

C247

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174019

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191405

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173217

Contributing_Source

ACC/AHA

NICHD

PCDC

DEFINITION

Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis.

FULL_SYN

ACE Inhibitor

Angiotensin-Converting Enzyme Inhibitor

angiotensin-converting enzyme inhibitor

Angiotensin-converting enzyme (ACE) inhibitor medication

ACE inhibitor

ACE-inhibitor

Has_ACC-AHA_SARS2_Authorized_Value

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49488

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49487

Is_PCDC_AML_Authorized_Value_For_Variable

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173319

label

ACE Inhibitor

Legacy Concept Name

ACE_Inhibitor

Preferred_Name

ACE Inhibitor

prefixIRI

Thesaurus:C247

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0003015

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C270

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C783

Delete Subject Author Type Created
No notes to display