Preferred Name |
ACE Inhibitor |
|
Synonyms |
ACE Inhibitor Angiotensin-Converting Enzyme Inhibitor angiotensin-converting enzyme inhibitor Angiotensin-converting enzyme (ACE) inhibitor medication ACE inhibitor ACE-inhibitor |
|
Definitions |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C247 |
|
Accepted_Therapeutic_Use_For |
Hypertension |
|
ALT_DEFINITION |
A medication that inhibits ACE, an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. A pharmaceutical agent that inhibits angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. It is primarily used for the reduction of proteinuria and the treatment of hypertension. |
|
CHEBI_ID |
CHEBI:35457 |
|
code |
C247 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C174019 |
|
Contributing_Source |
ACC/AHA NICHD PCDC |
|
DEFINITION |
Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. |
|
FULL_SYN |
ACE Inhibitor Angiotensin-Converting Enzyme Inhibitor angiotensin-converting enzyme inhibitor Angiotensin-converting enzyme (ACE) inhibitor medication ACE inhibitor ACE-inhibitor |
|
Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
|
Is_PCDC_AML_Authorized_Value_For_Variable | ||
label |
ACE Inhibitor |
|
Legacy Concept Name |
ACE_Inhibitor |
|
Preferred_Name |
ACE Inhibitor |
|
prefixIRI |
Thesaurus:C247 |
|
Semantic_Type |
Chemical Viewed Functionally |
|
UMLS_CUI |
C0003015 |
|
subClassOf |