loading...| Preferred Name |
Testolactone |
|
| Synonyms |
17Alpha-oxo-D-homo-1,4-androstadiene-3,17-dione TESTOLACTONE 1-Dehydrotestololactone 13-Hydroxy-3-0x0-13,17-secoandrosta-1,4-dien-17-oic Acid Delta-Lactone Therapeutic Testolactone Delta-1-Testololactone Testolactone D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione 1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic Acid Delta-Lactone Fludestrin SQ 9538 SQ-9538 Teslac |
|
| Definitions |
A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2301 |
|
| CAS_Registry |
968-93-4 |
|
| CHEBI_ID |
CHEBI:9460 |
|
| Chemical_Formula |
C19H24O3 |
|
| code |
C2301 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC |
|
| DEFINITION |
A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. (NCI04) |
|
| FDA_UNII_Code |
6J9BLA949Q |
|
| FULL_SYN |
17Alpha-oxo-D-homo-1,4-androstadiene-3,17-dione TESTOLACTONE 1-Dehydrotestololactone 13-Hydroxy-3-0x0-13,17-secoandrosta-1,4-dien-17-oic Acid Delta-Lactone Therapeutic Testolactone Delta-1-Testololactone Testolactone D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione 1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic Acid Delta-Lactone Fludestrin SQ 9538 SQ-9538 Teslac |
|
| Is_Value_For_GDC_Property | ||
| label |
Testolactone |
|
| Legacy Concept Name |
Testolactone |
|
| Maps_To |
Testolactone |
|
| NCI_Drug_Dictionary_ID |
42916 |
|
| NSC Number |
23759 |
|
| PDQ_Closed_Trial_Search_ID |
42916 |
|
| PDQ_Open_Trial_Search_ID |
42916 |
|
| Preferred_Name |
Testolactone |
|
| prefixIRI |
Thesaurus:C2301 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Hormone |
|
| UMLS_CUI |
C0039600 |
|
| subClassOf |